DrW 医学僧的科研日记 2022-06-20
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分享一篇于2021年10月在Nature communication上发表的使用通路特征预测转移性黑色素瘤患者免疫治疗效果的文章"Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blcade in metastatic melanoma",作者根据通路评分,使用弹性网络算法构建出Pathway-based signature,与其他已发表的明星signture相比,其预测效果更为稳定和准确。文章是如何使用通路构建出性能优异的预测模型呢?
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