需要试译，试译稿如下，共148单词：
In vivo, BAY 59-7939 showed a consistent and potent anti-coagulative and antithrombotic
effect. The anti-thrombotic effect was demonstrated in different thrombosis
models at 0.6-10 mg/kg given prophylactically depending on model and species. In
addition, 1 mg/kg iv BAY 59-7939 prolonged time to occlusion (> 30 min) in an
electrically injured carotid artery thrombosis model in rats. In a rat venous stasis model,
intravenous BAY 59-7939 inhibited thrombus formation with an ED50 of 0.1 mg/kg. In
addition, oral BAY 59-7939 (3.0 mg/kg) reduced thrombus growth in a treatment model in
rabbits. BAY 59-7939 provides also effective protection against thromboembolic death in
mice.

In safety pharmacology, BAY 59-7939, was tested for the potential occurrence of adverse
effects regarding cardiovascular, respiratory, CNS and renal function, lipid metabolism,
hematology, blood glucose concentrations, the gastrointestinal motility in vivo and the
effects on isolated guinea pig ileum and hERG mediated potassium channel in vitro.
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