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Villanova大学在全美大学排名前49, 与UIUC、里海大学、威斯康星麦德逊、俄亥俄州立、普渡齐名,排名超过宾州州立、华盛顿大学、马里兰、Rugters、RPI、德州 A&M、弗吉尼亚理工、天普大学等大学。作为全美最好的四所天主教私立大学之一,Villanova座立于费城西郊,环境优美。Villanova和大费城地区的制药公司有密切合作。
Villanova 化工系的黄博士(副教授)将于2022年夏/秋季招一个博士研究生以 研究和实验结合的计算方法以识别新颖的小分子抑制剂,以抑制导致人类疾病的蛋白质靶标。研究生将不断完善已有的计算平台,以结合了动力学和代谢建模、基因数据和 QSAR 模型,以识别潜在的小分子抑制剂,然后进行实验验证。黄博士的研究方法目前主要应用于T 细胞疗法(T cell therapy)、基因传输(gene delivery)和抗菌素耐药性病原体 (antimicrobial resistance pathogens). 他最近的代表论文可参看:
https://www.frontiersin.org/articles/10.3389/fmolb.2021.661424/full
https://www.mdpi.com/1422-0067/21/21/7814
https://pubs.acs.org/doi/10.1021/acsomega.0c00352
这个位置优先考虑具有生物细胞实验背景的学生。学生将会得到系统的计算编程训练。感兴趣欢迎把CV 发给他 (email:zuyi.huang@villanova.edu)。 Villanova大学对GRE和托福成绩有最低要求。
Dr. Zuyi (Jacky) Huang’s group in the Department of Chemical Engineering at Villanova University has an Ph.D. position available in Summer or Fall 2022. His lab identifies drug targets from omics data and developed a docking-based platform to discover small molecule inhibitors for drug targets that are responsible for human disease. His group has identified several patented chemical compounds that have potential to eliminate antimicrobial-resistant pathogens and inhibit a protease essential for COVID-19 replication.
The PhD candidate should have a B.S. or M.S. degree in biology-related disciplines. The on-going projects in Dr. Huang’s Systems Biology group include: 1) optimizing the growth of T cells for cancer research; 2) identifying small molecule inhibitors to enhance gene delivery; 3) screening natural compounds to treat foodborne pathogens or viruses. Preference will be given to the candidates with M.S. degree and bio-experiment experience. Interested applicants are encouraged to email their CVs to Dr. Huang (zuyi.huang@villanova.edu) for more detail. Villanova requires minimal GRE and TOEFL scores.
Villanova University is ranked #49 among the nation’s best colleges and universities by US News & World Report in its 2021 “Best Colleges” rankings. The university is located 12 miles from Philadelphia along the historic Main Line. Villanova University has a very strong basketball team. The Department of Chemical Engineering at Villanova has a good connection with local pharmaceutical companies.
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