https://www.jci.org/review_series/113Review Series
Tumor Microenvironment
Series edited by Andrew J Ewald
Cancer cells in a solid tumor are supported by vasculature, extracellular matrix, nerves, and an immunological milieu collectively known as the tumor microenvironment. Elements within the tumor microenvironment can act in a coordinated fashion to support tumor growth, immune evasion, and metastasis. In this series, reviews curated by Series Editor Andrew Ewald highlight the tumor microenvironment’s complex effects in cancer, describing its modulation of immune cells and the tumor stroma as well as its role in disseminating metastases.
Articles in series
Neutrophil dynamics in the tumor microenvironment
Amanda J. McFarlane, … , Seth B. Coffelt, Leo M. Carlin
Published March 15, 2021
Citation Information: J Clin Invest. 2021;131(6):e143759.
https://doi.org/10.1172/JCI143759.The dark side of daylight: photoaging and the tumor microenvironment in melanoma progression
Asurayya Worrede, … , Stephen M. Douglass, Ashani T. Weeraratna
Published March 15, 2021
Citation Information: J Clin Invest. 2021;131(6):e143763.
https://doi.org/10.1172/JCI143763.Exploiting bone niches: progression of disseminated tumor cells to metastasis
Aaron M. Muscarella, … , Sarah M. Waldvogel, Xiang H.-F. Zhang
Published March 15, 2021
Citation Information: J Clin Invest. 2021;131(6):e143764.
https://doi.org/10.1172/JCI143764.Leveraging microenvironmental synthetic lethalities to treat cancer
Kevin J. Metcalf, … , Zena Werb, Valerie M. Weaver
Published March 15, 2021
Citation Information: J Clin Invest. 2021;131(6):e143765.
https://doi.org/10.1172/JCI143765.--
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