Pp242 is mTORC1/C2 inhibitor Inhibits mTOR kinase with IC50 = 8 nM nad PI3 kinase (PI3K), with p110α IC50 = 2000 nM, p110b IC50 = 2200 nM, p110d IC50 = 100 nM, p110g IC50 = 1300 nM and DNA-PK IC50 = 410 nM
OSI-027(the mTOR C1/C2),INK-128(an mTOR C1/C2 inhibitor) is expected to be in clinic trials within one year.
谁有这里的OSI-07,INK-128的分子结构图?
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FROM 125.34.44.*